HCV-IN-45 [CAS 301211-35-8]

HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1].

[301211-35-8]

C16H19F3N6O3

400.36

FC(F)(COC1=NC(NC2=CC=C(C=C2)[N+]([O-])=O)=NC(NCCCCC)=N1)F

HCV

Room temperature