HCy-Lyso

HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm[1][2].

C24H30N2O

362.51

CC1(C(N(C2=CC=CC=C12)CC)/C=C/C3=CC=C(N4CCOCC4)C=C3)C

Fluorescent Dye

Room temperature