Helenalin [CAS 6754-13-8]

Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding[1][2].

[6754-13-8]

C15H18O4

262.31

O[C@H]1[C@]2([H])C(C(O[C@@]2(C[C@H]([C@@]([H])([C@]13C)C=CC3=O)C)[H])=O)=C

NF-κB

99.92

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H301

H301