HG-12-6 [CAS 2222354-57-4]

Size 1 Each

SKU:QM-0060455

Price on request

Quote Datasheet SDS COA

Product Details

Description
HG-12-6 is a type II inhibitor of IRAK4. HG-12-6 shows preferential binding to unphosphorylated inactive IRAK4 with an IC50 of 165 nM. HG-12-6 can modulate IRAK4 activity in autoimmunity and inflammation[1].
CAS Number
[2222354-57-4]
Molecular Formula
C29H27F3N6O2S
Molecular Weight
580.62
Smiles
O=C(NC1=CC=C(CN2CCNCC2)C(C(F)(F)F)=C1)C3=CC=CC(C4=CC=C5C(SC(NC(C6CC6)=O)=N5)=N4)=C3
Target
IRAK
Isoform
IRAK4
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
1 EachQM-0060455	1 EachQM-0060455 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

HG-12-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.