HIV-1 protease-IN-14

HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity[1].

C30H42N2O8S

590.73

O=C(N[C@H]([C@H](O)CN(S(=O)(C1=CC=C(OC(C)C)C=C1)=O)CC(C)C)CC2=CC=CC=C2)O[C@@H]3[C@H]4[C@H](OCC4)OC3

HIV Protease

Room temperature