HIV-1 protease-IN-5 [CAS 2525173-96-8]

HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].

[2525173-96-8]

C27H29F3N2O7S

582.59

C[C@H](CN(S(=O)(C1=CC=C(C=C1)C(F)(F)F)=O)C[C@H]([C@@H](NC(C2=CC(O)=C(C=C2)O)=O)CC3=CC=CC=C3)O)O

HIV Protease

10 mM in DMSO

Room temperature