HIV-1 protease-IN-9 [CAS 2925381-27-5]

HIV-1 protease-IN-9 (compound 5b) is a HIV-1 protease inhibitor, with a Ki of 0.028 nM. HIV-1 protease-IN-9 shows potent antiviral activity, with an IC50 of 66.8 nM[1].

[2925381-27-5]

C37H41N7O4S

679.83

CC1=C(C=C(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CN(CC(C)C)S(=O)(C3=CC=C(N)C=C3)=O)=O)C=C1)NC4=NC=CC(C5=CN=CC=C5)=N4

HIV Protease

10 mM in DMSO

Room temperature