HIV-IN-5 [CAS 2459929-62-3]

HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].

[2459929-62-3]

C30H24N2O8S

572.59

O=C(C1=CC=C(OCO2)C2=C1)OC3=CC=C(C(CSC4=NC(CC5=CC=C(OCO6)C6=C5)=C(CC)C(N4)=O)=O)C=C3

HIV

HIV-1

10 mM in DMSO

Room temperature