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HL389

HL389

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SKU:QM-0095498

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  • Description

    HL389 inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 μM and 9.66 μM. HL389 can be utilized as the ligand for E3 ligase for the synthesis of PROTAC degrader HL435.

  • Molecular Formula

    C22H19BrF3NO4

  • Molecular Weight

    498.29

  • Smiles

    BrC(C=C1)=CC(/C=C(C(C=CC(C(F)(F)F)=C2)=C2N3)\C3=O)=C1OCC(OC(C)(C)C)=O

  • Target

    Ligands for E3 Ligase

  • Isoform

    Cereblon

  • Shipping Conditions

    Room temperature

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HL389

HL389 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.