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HL389
HL389
SKU:QM-0095498
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Product Details
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Description
HL389 inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 μM and 9.66 μM. HL389 can be utilized as the ligand for E3 ligase for the synthesis of PROTAC degrader HL435.
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Molecular Formula
C22H19BrF3NO4
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Molecular Weight
498.29
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Smiles
BrC(C=C1)=CC(/C=C(C(C=CC(C(F)(F)F)=C2)=C2N3)\C3=O)=C1OCC(OC(C)(C)C)=O
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Target
Ligands for E3 Ligase
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Isoform
Cereblon
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Shipping Conditions
Room temperature
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HL389
HL389 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.