Name: HMGB1-IN-1
Brand: QuantiMol
SKU: QM-0151777-01
Price: 551.8 GBP
Availability: InStock

Product Details

Description
HMGB1-IN-1 (compound 6) displays strong NO inhibitory effect in RAW264.7 cells with IC50 value of 15.9 ± 0.6 μM. HMGB1-IN-1 inhibit the HMGB1/NF-κB/NLRP3 pathway. HMGB1-IN-1 shows good anti-inflammatory activity and good anti-sepsis effects in kidney injury[1].
Molecular Formula
C57H75N3O15
Molecular Weight
1042.22
Smiles
O=C(C=C1[C@@]2([C@@](CC[C@@]31C)(CC[C@@](C)(C2)C(OCC4=CN([C@@H]5O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]5OC(C)=O)N=N4)=O)C)[H])[C@@]6([C@@](CC[C@@H](C7(C)C)OC(/C=C/C8=CC=C(OC)C=C8)=O)(C7CC[C@@]36C)C)[H]
Target
Interleukin Related; NOD-like Receptor (NLR) ; TNF Receptor
Isoform
IL-1; NLRP3
Concentration
10mM
Purity
99.37
Solubility
DMSO : 125 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0151777-01	5 mgQM-0151777-01 £551.80/ea	£0.00	Quantity	£551.80/ea	£0.00

10 mgQM-0151777-02	10 mgQM-0151777-02 £853.12/ea	£0.00	Quantity	£853.12/ea	£0.00

10 mM - 1 mLQM-0151777-03	10 mM - 1 mLQM-0151777-03 £970.97/ea	£0.00	Quantity	£970.97/ea	£0.00

25 mgQM-0151777-04	25 mgQM-0151777-04 £1,656.23/ea	£0.00	Quantity	£1,656.23/ea	£0.00

50 mgQM-0151777-05	50 mgQM-0151777-05 £2,623.37/ea	£0.00	Quantity	£2,623.37/ea	£0.00

100 mgQM-0151777-06	100 mgQM-0151777-06 £4,166.42/ea	£0.00	Quantity	£4,166.42/ea	£0.00

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HMGB1-IN-1

HMGB1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.