HNPMI [CAS 1980848-48-3]

HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].

[1980848-48-3]

C22H20N2O3

360.41

CC1=CC=C(C(N2CCC3=C2C=CC=C3)C4=CC([N+]([O-])=O)=CC=C4O)C=C1

EGFR

99.57

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature