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SKU:QM-0139150-01
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Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM[1].
[172286-77-0]
C21H14N4O3
370.36
O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5
Others
10mM
99.82
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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Homocarbonyltopsentin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.