HPG1860 [CAS 2226133-29-3]

Name: HPG1860 [CAS 2226133-29-3]
Brand: QuantiMol
SKU: QM-0092332-01
Price: 484.97 GBP
Availability: InStock

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SKU:QM-0092332-01

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Product Details

Description
HPG1860 is an orally active, highly selective and potent FXR agonist, with an EC50 of 18 nM (FXR-luciferase reporter assay) . HPG1860 has EC50 values >30.0 μM for TGR5 and 13 other related nuclear receptors (cAMP biological assay) . HPG1860 can be used for the research of non-alcoholic steatohepatitis (NASH) [1].
CAS Number
[2226133-29-3]
Molecular Formula
C27H26Cl2N4O4S
Molecular Weight
573.49
Smiles
ClC(C=CC=C1Cl)=C1C2=NOC(C3CC3)=C2CN4C[C@H](N(C5=NC6=C(OC)C=C(C(O)=O)C=C6S5)CC4)C
Target
Aminotransferases (Transaminases) ; FXR
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0092332-01	1 mgQM-0092332-01 £484.97/ea	£0.00	Quantity	£484.97/ea	£0.00

5 mgQM-0092332-02	5 mgQM-0092332-02 £1,356.13/ea	£0.00	Quantity	£1,356.13/ea	£0.00

10 mgQM-0092332-03	10 mgQM-0092332-03 £2,139.80/ea	£0.00	Quantity	£2,139.80/ea	£0.00

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HPG1860 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.