HPK1-IN-27 [CAS 2268794-52-9]

HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1) . MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38) [1].

[2268794-52-9]

C26H23F3N4O4

512.48

OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1

MAP4K

10 mM in DMSO

Room temperature