HSD17B13-IN-94 [CAS 2848620-90-4]

HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol. HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI).

[2848620-90-4]

C21H20ClN3O4S

445.92

OC1=CC=C(C(NC2=C(C(NCCC3=C(OC)C=CC=C3)=O)N=C(C)S2)=O)C=C1Cl

17β-HSD; Estrogen Receptor/ERR

10 mM in DMSO

Room temperature