Human IL10 mRNA encodes the human interleukin 10 (IL10) protein, a cytokine that produces primarily by monocytes and to a lesser extent by lymphocytes. IL10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production.
