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HW091077 [CAS 2766757-56-4]

HW091077 [CAS 2766757-56-4]

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QM-0015224

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Product Details

  • Description

    HW091077 is a highly selective P2X3 receptor antagonist with an IC50 of 17 nM. HW091077 blocks ATP-induced calcium influx and cell depolarization to inhibit cough reflex pathways. HW091077 is promising for research of chronic cough[1].

  • CAS Number

    [2766757-56-4]

  • Molecular Formula

    C22H22F4N4O3S

  • Molecular Weight

    498.49

  • Smiles

    FC1=C(C2=NC=C(C)S2)C=C(C=C1C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)O[C@@H](C)[C@@H](O)C

  • Target

    P2X Receptor

  • Isoform

    P2X2 Receptor

  • Shipping Conditions

    Room temperature
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1 EachQM-0015224
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HW091077 [CAS 2766757-56-4]

HW091077 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.