Hydrochlorothiazide [CAS 58-93-5]
Hydrochlorothiazide [CAS 58-93-5]
SKU:QM-0157865-01
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Product Details
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Description
Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].
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CAS Number
[58-93-5]
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Molecular Formula
C7H8ClN3O4S2
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Molecular Weight
297.75
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Smiles
O=S(C1=C(Cl)C=C(C2=C1)NCNS2(=O)=O)(N)=O
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Target
Potassium Channel; TGF-beta/Smad
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Purity
99.46
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Hydrochlorothiazide [CAS 58-93-5]
Hydrochlorothiazide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.