β-Hydroxyisovalerylshikonin [CAS 7415-78-3]
β-Hydroxyisovalerylshikonin [CAS 7415-78-3]
SKU:QM-0165625-01
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Product Details
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Description
Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1].
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CAS Number
[7415-78-3]
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Molecular Formula
C21H24O7
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Molecular Weight
388.41
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Smiles
CC(C)(O)CC(O[C@@H](C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)=O
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Target
EGFR; Src
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Purity
99.83
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Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H315, H317, H319
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Precautions
H301, H315, H317, H319
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β-Hydroxyisovalerylshikonin [CAS 7415-78-3]
β-Hydroxyisovalerylshikonin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.