Hypaphorine [CAS 487-58-1]

Hypaphorine is an indole found in Caragana korshinskii. Hypaphorine has neurological and glucose-lowering effects. Hypaphorine prevents Lipopolysaccharides (LPS) -mediated acute lung injury (ALI) and proinflammatory response via inactivating the p38/JNK signaling pathway by upregulating DUSP1[1][2][3][4].

[487-58-1]

C14H18N2O2

246.31

C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC2=CC=CC=C12

JNK; p38 MAPK

99.93

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature

H301, H311, H331

H301, H311, H331