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SKU:QM-0155516-01
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I-BET282 is a pan-inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC50s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD) [1].
[1422554-34-4]
C25H30N4O4
450.53
COC1=C(C2=C(C)ON=C2C)C=C(N=CC3=C4N(C(C5CCOCC5)=N3)[C@@H](COC)C)C4=C1
Epigenetic Reader Domain
98.9
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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I-BET282 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.