ICI 169369 (free base) [CAS 85273-95-6]

ICI 169369 (free base) is an orally active, selective and non-competitive antagonist against 5HT receptor. ICI 169369 (free base) blunts the vasopressin (AVP), but not the ACTH, prolactin or growth hormone reponses to insulin-induced hypoglycaemia. ICI 169369 (free base) blocks centrally mediated 5-HT responses and lowers portal pressure in portal hypertensive rats[1][2][3][4].

[85273-95-6]

C19H20N2S

308.44

CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3

5-HT Receptor

Room temperature