ICI-200880 [CAS 105080-50-0]

ICI-200880 is a potent, selective and reversible human neutrophil elastase (HNE) inhibitor. ICI-200880 is promising for research of inflammatory lung diseases related to neutrophil elastase, such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) [1].

[105080-50-0]

C30H34ClF3N4O7S

687.13

O=C(C1=CC=C(C(NS(=O)(C2=CC=C(Cl)C=C2)=O)=O)C=C1)N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(NC(C(C)C)C(C(F)(F)F)=O)=O)=O

Elastase

Room temperature