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Icilin [CAS 36945-98-9]

Icilin [CAS 36945-98-9]

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SKU:QM-0136868-01

£68.47 GBP
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  • Description

    Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM) . Icilin is a "super-cooling agent" [1][2]. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response[3].

  • CAS Number

    [36945-98-9]

  • Molecular Formula

    C16H13N3O4

  • Molecular Weight

    311.29

  • Smiles

    O=C1N(C2=CC=CC=C2O)CC=C(C3=CC=CC([N+]([O-])=O)=C3)N1

  • Target

    TRP Channel

  • Isoform

    TRPM8

  • Concentration

    10mM

  • Purity

    99.26

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H312, H332

  • Precautions

    H302, H312, H332

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Variant Variant total Quantity Price Variant total
5 mgQM-0136868-01
5 mgQM-0136868-01
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10 mM - 1 mLQM-0136868-02
10 mM - 1 mLQM-0136868-02
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10 mgQM-0136868-03
10 mgQM-0136868-03
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50 mgQM-0136868-04
50 mgQM-0136868-04
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100 mgQM-0136868-05
100 mgQM-0136868-05
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500 mgQM-0136868-06
500 mgQM-0136868-06
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Icilin [CAS 36945-98-9]

Icilin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.