IDX375 [CAS 1162665-52-2]

IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1].

[1162665-52-2]

C24H37N4O6PS

540.61

CS(=O)(NC1=CC=C(C2=C1)NC(C3=C(O)[C@H](C(C)(C)C)N(CCC(C)(C)C)C3=O)=N[P@]2(OCC)=O)=O

Endogenous Metabolite

Room temperature