IKKβ-IN-3

IKKβ-IN-3 (Compound hit4) is a IKKβ inhibitor with an IC50 value of 30.4 nM. IKKβ is a key enzyme in the NF-κB signaling pathway and is involved in the development of many diseases. IKKβ-IN-3 can be used in the study of CAF-induced arthritis[1].

C18H27NO4

321.41

CC(C[C@H](NC(C[C@H](CC(CC1=CC=CC=C1)=O)O)=O)CO)C

IKK

IKK-β

10 mM in DMSO

Room temperature