ILK-IN-2 [CAS 1333146-24-9]

Name: ILK-IN-2 [CAS 1333146-24-9]
Brand: QuantiMol
SKU: QM-0155065-01
Price: 200.66 GBP
Availability: InStock

Size 2 mg 5 mg 10 mM - 1 mL 10 mg 25 mg

SKU:QM-0155065-01

£200.66 GBP

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Product Details

Description
ILK-IN-2 (OSU-T315 analog) is an oral PDK2 inhibitor and also an ILK inhibitor, with an IC50 of 0.6 μM. ILK-IN-2 induces cell autophagy and apoptosis, showing anti-tumor activity. ILK-IN-2 directly abolishes AKT activation by preventing AKT from translocating to lipid rafts, triggering Caspase-dependent apoptosis in chronic lymphocytic leukemia (CLL) and extending the lifespan in TCL1 mouse models[1][2].
CAS Number
[1333146-24-9]
Molecular Formula
C30H30F3N5O
Molecular Weight
533.59
Smiles
O=C(NC)CCC1=NN(C2=CC=C(N3CCNCC3)C=C2)C(C4=CC=C(C5=CC=C(C(F)(F)F)C=C5)C=C4)=C1
Target
Ser/Thr Kinase
Purity
99.41
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

Your cart
Variant	Variant total	Quantity	Price	Variant total
2 mgQM-0155065-01	2 mgQM-0155065-01 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

5 mgQM-0155065-02	5 mgQM-0155065-02 £351.32/ea	£0.00	Quantity	£351.32/ea	£0.00

10 mM - 1 mLQM-0155065-03	10 mM - 1 mLQM-0155065-03 £403.56/ea	£0.00	Quantity	£403.56/ea	£0.00

10 mgQM-0155065-04	10 mgQM-0155065-04 £527.50/ea	£0.00	Quantity	£527.50/ea	£0.00

25 mgQM-0155065-05	25 mgQM-0155065-05 £928.45/ea	£0.00	Quantity	£928.45/ea	£0.00

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ILK-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.