Illudin B [CAS 134857-03-7]

Illudin B is a DNA-targeting cytotoxin that forms interstrand DNA crosslinks via covalent binding, disrupting DNA replication and transcription. Illudin B induces cell cycle arrest and apoptosis, showing toxicity against multiple tumor cells (e.g., leukemia, breast, lung cancer) [1].

[134857-03-7]

C15H22O5

282.33

C[C@]1(C2(CC2)[C@@](O)(C(C3=C1[C@H](C(C)([C@H]3O)C)O)=O)C)O

Apoptosis; DNA/RNA Synthesis

Room temperature