Indantadol [CAS 202844-10-8]

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SKU:QM-0002367

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Description
Indantadol (the free base of CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol completely inhibits dopamine release caused by NMDA. Indantadol protects neurons, with an ED₅₀ of 35 μM. Indantadol has anticonvulsant and anti-high pain hypersensitivity activities[1][2][3].
CAS Number
[202844-10-8]
Molecular Formula
C11H14N2O
Molecular Weight
190.24
Smiles
O=C(N)CNC1CC2=C(C=CC=C2)C1
Target
IGluR; Monoamine Oxidase
Isoform
NMDA Receptor
Shipping Conditions
Room temperature
Hazard Statement
H315-H319-H320
Precautions
P264-P280-P302+P352-P305+P351+P338-P362

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Indantadol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.