Indinavir (sulfate) [CAS 157810-81-6]
Indinavir (sulfate) [CAS 157810-81-6]
SKU:QM-0158799-01
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Product Details
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Description
Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CLpro inhibitor[1][2][3][4].
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CAS Number
[157810-81-6]
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Molecular Formula
C36H49N5O8S
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Molecular Weight
711.87
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Smiles
O=C([C@@H](C[C@H](O)CN(CCN(CC1=CN=CC=C1)C2)[C@@H]2C(NC(C)(C)C)=O)CC3=CC=CC=C3)N[C@H]4C(C=CC=C5)=C5C[C@H]4O.O=S(O)(O)=O
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Target
Apoptosis; HIV; HIV Protease; MMP; SARS-CoV
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Isoform
HIV-1; MMP-2
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Purity
99.97
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Solubility
DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Indinavir (sulfate) [CAS 157810-81-6]
Indinavir (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.