Indoline is a derivative of Indole. Indoline can use as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the HIV-1 envelope glycoprotein (Env) in advance, and causes viral inactivation. Indoline binds to gp120. Indoline CD4mcs can inhibit HIV-1AD8 with an IC50 in the micromolar range[1].
CAS Number
[496-15-1]
Molecular Formula
C8H9N
Molecular Weight
119.17
Smiles
C12=C(NCC2)C=CC=C1
Target
HIV
Concentration
10mM
Purity
99.89
Solubility
DMSO : ≥ 200 mg/mL
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)