INOs-IN-6

INOs-IN-6 is an anti-inflammatory agent. iNOs-IN-6 inhibits NF-κB, iNOS, and MAPK expression (IC50: 0.2-0.62 μM) . iNOs-IN-6 reduces IL-6, TNF-α, and IL-1β pro-inflammatory mediators levels (IC50: 0.4-0.69 μM) [1].

C20H16ClN3O2S

397.88

ClC1=CC=C(NC(C2=C(C)NC(NC2C3=CC4=C(C=CC=C4)S3)=O)=O)C=C1

Interleukin Related; NF-κB; NO Synthase; p38 MAPK

Room temperature