Integrin-IN-2 [CAS 2378617-67-3]

Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively[1].

[2378617-67-3]

C27H30N4O3

458.55

O=C(O)CC(C1=CC=CC(C2CC2)=C1)NC3=NC=C(OCCC4=NC5=C(CCCN5)C=C4)C=C3

Integrin

95.71

10 mM in DMSO

4°C (Powder, protect from light)

Room Temperature