Name: IRAK4-IN-14 [CAS 2667681-71-0]
Brand: QuantiMol
SKU: QM-0148856-01
Price: 426.65 GBP
Availability: InStock

Product Details

Description
IRAK4-IN-14 (compound 28) is a potent, selective and orally active IRAK4 inhibitor with an IC50 of 0.003 μM. IRAK4-IN-14 shows good PK parameters in rats and mouse. IRAK4-IN-14 shows synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL in combination with Acalabrutinib[1].
CAS Number
[2667681-71-0]
Molecular Formula
C25H28FN9O
Molecular Weight
489.55
Smiles
CC1=NC=C(C2=NC3=C(OC4(C)CC4)N=C(NC5=CN(C6CCN(C)CC6)N=C5)N=C3C=C2F)C=N1
Target
IRAK
Isoform
IRAK4
Purity
99.01
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0148856-01	5 mgQM-0148856-01 £426.65/ea	£0.00	Quantity	£426.65/ea	£0.00

10 mM - 1 mLQM-0148856-02	10 mM - 1 mLQM-0148856-02 £455.81/ea	£0.00	Quantity	£455.81/ea	£0.00

10 mgQM-0148856-03	10 mgQM-0148856-03 £652.64/ea	£0.00	Quantity	£652.64/ea	£0.00

25 mgQM-0148856-04	25 mgQM-0148856-04 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

50 mgQM-0148856-05	50 mgQM-0148856-05 £1,870.07/ea	£0.00	Quantity	£1,870.07/ea	£0.00

100 mgQM-0148856-06	100 mgQM-0148856-06 £2,873.66/ea	£0.00	Quantity	£2,873.66/ea	£0.00

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IRAK4-IN-14 [CAS 2667681-71-0]

IRAK4-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.