IRAK4-IN-32

IRAK4-IN-32 (Compound 10) is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an enzymatic IC50 value of 18.86 nM and a cellular IC50 value of 6.19 nM. IRAK4-IN-32 is promising for research of inflammatory and autoimmune diseases[1].

C18H16ClN7O2S

429.88

CS(=O)(C1=CC=CC=C1NC2=NC(NC3=CC=C(N=C3)CO)=NC=C2Cl)=NC#N

IRAK

IRAK4

Room temperature