Irinotecan-d10 [CAS 718613-28-6]

Irinotecan-d10 is a deuterium labeled Irinotecan ((+) -Irinotecan) . Irinotecan ((+) -Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1].

[718613-28-6]

C33H28D10N4O6

596.74

CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(N6CCC(N7C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C7([2H])[2H])CC6)=O)C=C51

Autophagy; Topoisomerase

98.02

10 mM in DMSO

4°C (Powder, protect from light)

Room Temperature