Name: Iruplinalkib [CAS 1854943-32-0]
Brand: QuantiMol
SKU: QM-0148608-01
Price: 238.32 GBP
Availability: InStock

Product Details

Description
Iruplinalkib (WX-0593) is an orally active and selective ALK/ROS1 inhibitor. Iruplinalkib can effectively inhibit tyrosine autophosphorylation of ALK and mutant ALK, EGFR, with the IC50 between 5.38 and 16.74 nM. Iruplinalkib is also a suppressive agent of the transporter MATE1, MATE2K, P-gp and BCRP. Iruplinalkib can be used in the study of non-small cell lung cancer[1][2].
CAS Number
[1854943-32-0]
Molecular Formula
C29H38ClN6O2P
Molecular Weight
569.08
Smiles
O=P(C)(C)C1=C(NC2=NC(NC3=CC=C(N4CCC5(CCN(CC5)C)CC4)C=C3OC)=NC=C2Cl)C=CC=C1
Target
Akt; Anaplastic lymphoma kinase (ALK) ; BCRP; ERK; ROS Kinase; STAT
Purity
99.62
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0148608-01	5 mgQM-0148608-01 £238.32/ea	£0.00	Quantity	£238.32/ea	£0.00

10 mgQM-0148608-02	10 mgQM-0148608-02 £363.47/ea	£0.00	Quantity	£363.47/ea	£0.00

25 mgQM-0148608-03	25 mgQM-0148608-03 £678.15/ea	£0.00	Quantity	£678.15/ea	£0.00

50 mgQM-0148608-04	50 mgQM-0148608-04 £928.45/ea	£0.00	Quantity	£928.45/ea	£0.00

100 mgQM-0148608-05	100 mgQM-0148608-05 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

1 gQM-0148608-06	1 gQM-0148608-06 £3,690.14/ea	£0.00	Quantity	£3,690.14/ea	£0.00

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Iruplinalkib [CAS 1854943-32-0]

Iruplinalkib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.