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ISRIB (trans-isomer) [CAS 1597403-47-8]
ISRIB (trans-isomer) [CAS 1597403-47-8]
SKU:QM-0141373-01
£121.75 GBP
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![ISRIB (trans-isomer) [CAS 1597403-47-8]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
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Description
ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM) .
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CAS Number
[1597403-47-8]
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Molecular Formula
C22H24Cl2N2O4
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Molecular Weight
451.34
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Smiles
O=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
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Target
Apoptosis; Autophagy; PERK
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Purity
99.49
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Solubility
DMSO : 4.55 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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ISRIB (trans-isomer) [CAS 1597403-47-8]
ISRIB (trans-isomer) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.