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SKU:QM-0143088-01
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Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
[873054-44-5]
C24H28N2O3
392.49
CC(C)(C1=C(C=C(C(C(C)(C)C)=C1)O)NC(C2=CNC3=C(C2=O)C=CC=C3)=O)C
Autophagy; CFTR
99.97
DMSO : 50 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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Ivacaftor is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.