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J-1048 [CAS 2374772-60-6]

J-1048 [CAS 2374772-60-6]

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QM-0068354

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Product Details

  • Description

    J-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-β/Smad signaling pathway[1].

  • CAS Number

    [2374772-60-6]

  • Molecular Formula

    C23H17FN6S2

  • Molecular Weight

    460.55

  • Smiles

    FC1=CC(NC(CN2C=C(C3=CC4=NSN=C4C=C3)C(C5=CC=CC(C)=N5)=N2)=S)=CC=C1

  • Target

    Anaplastic lymphoma kinase (ALK)

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature
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J-1048 [CAS 2374772-60-6]

J-1048 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.