JBJ-02-112-05 [CAS 2748162-29-8]

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SKU:QM-0062832

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Description
JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 15 nM for EGFRL858R/T790M[1].
CAS Number
[2748162-29-8]
Molecular Formula
C27H20N4O2S
Molecular Weight
464.54
Smiles
O=C(NC1=NC=CS1)C(N2C(C(C=C(C3=CC(C=CN4)=C4C=C3)C=C5)=C5C2)=O)C6=CC=CC=C6
Target
EGFR
Isoform
EGFR/ErbB1/HER1
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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JBJ-02-112-05 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.