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JH-IX-179 [CAS 1939104-08-1]
JH-IX-179 [CAS 1939104-08-1]
SKU:QM-0005161
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Product Details
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Description
JH-IX-179 is an FLT3 inhibitor (IC50 = 4 nM (FLT3-ITD), 10 nM (FLT3-D835Y) ) . JH-IX-179 inhibits G1 phase arrest and induces apoptosis in FLT3-ITD-expressing cells. JH-IX-179 can be used in acute myeloid leukemia (AML) research[1].
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CAS Number
[1939104-08-1]
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Molecular Formula
C26H24N6O
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Molecular Weight
436.51
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Smiles
O=C1C2=C(C(N3)=C1C4=C3C=C(C5=CNN=C5)C=C4)C=C(C6=CN(CCCN(C)C)N=C6)C=C2
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Target
Apoptosis; FLT3
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Shipping Conditions
Room temperature
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JH-IX-179 [CAS 1939104-08-1]
JH-IX-179 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.