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SKU:QM-0137358-01
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JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.
[1639422-97-1]
C28H27N5O2
465.55
O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1
Anaplastic lymphoma kinase (ALK)
10mM
98.98
DMSO : ≥ 25 mg/mL
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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JH-VIII-157-02 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.