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JHD205

JHD205

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QM-0093474

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Product Details

  • Description

    JHD205 is a CDK4/6 inhibitor that induces apoptosis and DNA damage. JHD205 inhibits DNA repair by upregulating Caspase3 and p-H2AX. JHD205 has superior potency to Abemaciclib in a xenograft chick embryo breast cancer model.[1].

  • Molecular Formula

    C32H40F2N8O

  • Molecular Weight

    590.71

  • Smiles

    COC1=CC(N2CCC(CC2)N3CCN(CC3)C)=CC=C1NC4=NC(C5=CC(F)=C6C(N(C(C)=N6)C(C)C)=C5)=C(C=N4)F

  • Target

    CDK

  • Shipping Conditions

    Room temperature
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1 EachQM-0093474
1 EachQM-0093474
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JHD205

JHD205 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.