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SKU:QM-0139086-01
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JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].
[2234281-75-3]
C22H24N2O3
364.44
O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC
Notch
98
DMSO : 125 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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JI051 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.