JNJ-26146900 [CAS 868691-50-3]

JNJ-26146900 is a potent and orally active androgen receptor antagonist with a Ki value of 400nM for rat AR. JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand. JNJ-26146900 reduces prostate tumor size and prevents bone loss. JNJ-26146900 can be used in research of cancer[1].

[868691-50-3]

C15H15F3N2O3S

360.35

N#CC1=CC2=C(C=C1C(F)(F)F)NC([C@@](O)(CS(=O)(CC)=O)C)=C2

Androgen Receptor

10 mM in DMSO

Room temperature