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JNJ-40418677 [CAS 1146594-87-7]

JNJ-40418677 [CAS 1146594-87-7]

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QM-0079499-01

£67.44 GBP
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Product Details

  • Description

    JNJ-40418677 is an orally active modulator of γ-secretase, can cross the blood-brain barrier. JNJ-40418677 inhibits Aβ42 and NS2B-NS3 protease, with IC50s of 200 nM and 3.9 μM, respectively. JNJ-40418677 displays good biological tolerance, can be use for Alzheimer’s disease research[1][2][3].

  • CAS Number

    [1146594-87-7]

  • Molecular Formula

    C26H22F6O2

  • Molecular Weight

    480.44

  • Smiles

    CC(C)C[C@@H](C1=CC(C2=CC=C(C=C2)C(F)(F)F)=CC(C3=CC=C(C=C3)C(F)(F)F)=C1)C(O)=O

  • Target

    Amyloid-β; γ-secretase

  • Purity

    99.48

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H300

  • Precautions

    H300
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Variant Variant total Quantity Price Variant total
1 mgQM-0079499-01
1 mgQM-0079499-01
£67.44/ea		 £0.00
£67.44/ea £0.00
5 mgQM-0079499-02
5 mgQM-0079499-02
£238.32/ea		 £0.00
£238.32/ea £0.00
10 mM - 1 mLQM-0079499-03
10 mM - 1 mLQM-0079499-03
£249.26/ea		 £0.00
£249.26/ea £0.00
10 mgQM-0079499-04
10 mgQM-0079499-04
£351.32/ea		 £0.00
£351.32/ea £0.00
25 mgQM-0079499-05
25 mgQM-0079499-05
£715.82/ea		 £0.00
£715.82/ea £0.00
50 mgQM-0079499-06
50 mgQM-0079499-06
£1,179.95/ea		 £0.00
£1,179.95/ea £0.00
100 mgQM-0079499-07
100 mgQM-0079499-07
£1,970.91/ea		 £0.00
£1,970.91/ea £0.00
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JNJ-40418677 [CAS 1146594-87-7]

JNJ-40418677 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.