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SKU:QM-0139178-01
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JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
[1627902-21-9]
C18H13ClF4N6O
440.78
ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F
P2X Receptor
P2X7 Receptor
10mM
99.3
DMSO : 62.5 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302
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JNJ-54175446 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.