JNJ-6204 [CAS 2765264-50-2]

JNJ-6204 is a dual inhibitor for CSNK1D (Casein Kinase 1 Delta) and CSNK1E (Casein Kinase 1 Epsilon) (CSNK1D IC50=2.3 nM; CSNK1E IC50=137 nM) . JNJ-6204 shows good brain exposure[1][2].

[2765264-50-2]

C19H11D6FN6O

370.41

FC1=CC=C(N=C1)C2=NN3C(COC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C3)=C2C4=C5C(NN=C5)=NC=C4

Casein Kinase

99.75

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice