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(+) -JQ-1 [CAS 1268524-70-4]

(+) -JQ-1 [CAS 1268524-70-4]

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QM-0143159-01

£78.82 GBP
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Product Details

  • Description

    (+) -JQ-1 (JQ1), a chemical probe, is a potent, specific, and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4 (1/2) ) [1]. (+) -JQ-1 also activates autophagy[2].

  • CAS Number

    [1268524-70-4]

  • Molecular Formula

    C23H25ClN4O2S

  • Molecular Weight

    456.99

  • Smiles

    O=C(C[C@H]1C2=NN=C(N2C3=C(C(C4=CC=C(C=C4)Cl)=N1)C(C)=C(S3)C)C)OC(C)(C)C

  • Target

    Autophagy; Epigenetic Reader Domain; Ligands for Target Protein for PROTAC

  • Isoform

    BRD4

  • Purity

    99.9

  • Solubility

    DMSO : ≥ 45 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
2 mgQM-0143159-01
2 mgQM-0143159-01
£78.82/ea		 £0.00
£78.82/ea £0.00
5 mgQM-0143159-02
5 mgQM-0143159-02
£106.00/ea		 £0.00
£106.00/ea £0.00
10 mM - 1 mLQM-0143159-03
10 mM - 1 mLQM-0143159-03
£115.00/ea		 £0.00
£115.00/ea £0.00
10 mgQM-0143159-04
10 mgQM-0143159-04
£129.63/ea		 £0.00
£129.63/ea £0.00
50 mgQM-0143159-05
50 mgQM-0143159-05
£275.99/ea		 £0.00
£275.99/ea £0.00
100 mgQM-0143159-06
100 mgQM-0143159-06
£363.47/ea		 £0.00
£363.47/ea £0.00
500 mgQM-0143159-07
500 mgQM-0143159-07
£878.63/ea		 £0.00
£878.63/ea £0.00
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(+) -JQ-1 [CAS 1268524-70-4]

(+) -JQ-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.